Mounting epidemiological and experimental evidence consistently indicates that obesity is a robust risk factor, with 50~100% increase in risk for CRC. As obesity has reached an epidemic level and increases in the scope of the problem are projected, it is critical to understand the mechanism(s) responsible for the link and thereby to develop preventive strategies. The ultimate goal is, through the completion of this project, to facilitate the development of preventive approaches to diminish dietary obesity associated CRC.
Department of Food Science
The safety of the food supply is a continuing issue for agriculture, with an estimated 81 million instances of food borne illnesses in the USA annually, with an estimated cost of $152 billion dollars per year to the US economy. The Center for Disease Control and prevention estimates that 46% of these illnesses were due to produce - thus food safety is very much an agricultural issue.
There is a strong association of chronic inflammation with various types of diseases.
Plants are capable of producing a great diversity of relatively small organic chemicals that are called “secondary”, or, more recently, “specialized” metabolites, because they are not involved in central metabolism (Gang, 2005; Weng and Noel, 2012). Currently, well over 200,000 distinct molecules are known to be produced by plants and found to serve many important roles. As pigments, scents, and flavors they attract pollinators and seed dispersers (Gang, 2005).