Laminitis is a crippling disease that affects about one-percent of the more than nine million horses in North America. The cost of laminitis to the horse industry exceeds $1 billion annually, predominantly from loss of use of the affected animals rather than medical costs. Laminitis results from failure of the digital laminae, which suspend a horse's distal phalanx, and thus the axial skeleton and all that is attached to it, within the hoof capsule. The laminae are composed of a hoof wall-associated epidermal layer and a distal phalanx-associated dermal layer.
Massachusetts Agricultural Experiment Station
Invasive plants in forest understories in Massachusetts threaten native ecosystems and working forests. This research will use satellite remote sensing to map three understory invasive species (buckthorn, honeysuckle, and barberry) in western Massachusetts. Occurrence maps will be compared to geology, topography, and land use to better identify correlates of invasion across the landscape and create maps identifying high invasion risk.
This project will study and numerically model road salt impact on water quality in a typical aquifer in eastern Massachusetts. The study area is a public water well field in the Town of Norwell presently instrumented with 3 multiparameter sensors at different aquifer depths and one sensor located in the nearby stream. The well field is within a glacial outwash area with simple subsurface geology and lies a short distance from major road salt sources including MA Rt. 3, a mall, and lies downstream from a road salt storage shed.
Invasive plants lead to the loss of crop revenue in agricultural systems, damage native habitats and wildlife populations, and alter ecosystem services such as nutrient cycling. This project will map the abundance of 13 problematic invasive plants across the northeastern United States by collecting expert knowledge. We will then predict invasion risk based on current climactic suitability, as well as future risk associated with climate change.
Type 2 diabetes mellitus has increased by about 33% over the past decade in the United States, generating higher health care costs, and is related to obesity. Some women undergoing menopause gain belly fat and may have a tendency to develop diabetes. The researchers have shown that a daily soy supplement containing phytoestrogens (weak estrogen-like chemicals) reduces the amount of belly fat in women after menopause compared to a milk shake placebo. Most fat reduction is superficial, but there is also some reduction of deeper belly fat located near abdominal organs.
The genes within the genome (genetic code) of cattle need to be identified and defined before variability of these genes among cattle (individuals and breeds) can be identified. One goal is to determine whether such variations when found are associated with enhanced or decreased resistance to infectious diseases. The cattle genome has been largely sequenced (that is, the genetic code 'read'), and now one of the purposes of the international community effort is to annotate the bovine genome (define genes within the genetic code).
Evaluate pasture management systems with beef and other livestock.
Cancer is a leading cause of human death around the world. It was estimated that 30-70-percent of all cancer cases might be preventable by dietary modification, depending on the dietary components and specific type of cancer. Epidemiological evidence indicates that a diet abundant in fruits and vegetables may reduce the risk of cancer in some individuals, and this effect has been attributed to bioactive components present in these foods. Many bioactive food components have been studied intensively for possible cancer preventive effects.
The profile of dietary lipids in humans has changed dramatically as agricultural practices have advanced. This change has resulted in major changes in the consumption of omega-6 and omega-3 fatty acids. Our ancestors ingested concentrations of these two classes of fatty acids in a 7:1 ratio (comparing dietary omega-6 to omega-3). In Western cultures, the ratio in currently 25:1. This change in dietary lipids is problematic since humans are not able to interconvert (convert from one to the other) omega-6 and omega-3 fatty acids.
Dietary factors are important predictors of long term health and the incidence of chronic disease. Laboratory methods will be employed, primarily in vitro models, such as in vitro digestion and tissue cultures, which will be used to evaluate the bioactivity of nutrients and other food bioactives to understand the mechanisms. The investigator will seek to advance the science of defining the role of bioactive dietary constituents for optimal human health. This will provide fertile grounds for ongoing collaborations and future collaborative research and grant proposal development.