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Fly Management in Animal Agriculture Systems and Impacts on Animal Health and Food Safety

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Principal Investigator/Project Leader: 
Co-Principal Investigator/Co-Project Leader: 
Kristen
DeAngelis
Department of Project: 
Department of Microbiology
Project Description: 

The diverticulated crop organ of the common house fly, which is the major insect vector of numerous human food pathogens (e.g., Escherichia coli) is the major reservoir or storage area for this, and other, important food pathogens. It has also been demonstrated that this is where horizontal transmission of antibiotic resistance to E. coli occurs. Thus, the diverticulated crop organ is an essential component in the transmission cycle between pathogens and human foods/food crops. At the same time, the salivary glands of house fly are directly involved in vectoring pathogens and, are intimately involved in pathogen transmission. Almost nothing is known about the physiological factors involved in the regulation of both crop filling and emptying of the adult house fly. Even more concerning is that we know even less about the effect of various pathogens, either food pathogens or pathogens of the house fly vector, on salivary gland regulation. What effect does the salivary gland hypertrophy
virus have on normal crop organ function? A better understanding of how these two essential organ systems are regulated, will give researchers a better picture of how to use this information to explore novel, non-chemical control strategies that can be directed at interfering with the normal regulation of these two organ systems. Ultimately, non-traditional control strategies will be developed that rely on interfering with the function of these two organ systems, both of which are essential to the fly. It is the objective of this project to develop non-traditional control strategies, thus reducing fly resistance to insecticides. Thus, by compromised longevity of the vector, pathogen vectoring, and/or reproductive development of the flies can be interfered with resulting in death, abnormal flight ability, and or reduced fecundity.

Topics: 
Agriculture topics: 
Diseases
Integrated Pest Management
Livestock