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Food Bioactives for Protection Against Inflammatory Diseases

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Principal Investigator/Project Leader: 
Co-Principal Investigator/Co-Project Leader: 
Department of Project: 
Department of Food Science
Project Description: 

There is a strong association of chronic inflammation with various types of diseases.

However, many of the current treatments for chronic inflammation are limited due to undesirable side effects associated with their long-term use and research has shown bioactive dietary components to be promising candidates for the prevention of inflammation and associated diseases. Thus, the goal of this project is to investigate the role of food bioactives in conjunction with microbiomes in prevention of inflammatory responses.  Inflammation is part of the body’s defense responses to harmful stimuli.  For example, chronic inflammation has tumor-promoting effects by various mechanisms including enhancing proliferation of malignant cells, promoting tumor angiogenesis and metastasis, and altering tumor response to chemotherapeutic drugs [1]. Thus, there is great interest and need to control improper inflammatory responses. However, many of the current treatment modalities for chronic inflammation are limited due to undesirable side effects associated with their long-term use [2]. Research has shown bioactive dietary components to be powerful manipulators in the prevention and early treatment of inflammation [3].

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